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Artigo 18 - PREVALENCE OF MALIGNANT

Purpose:

Type I neurofibromatosis (NF1) is considered the most common “new” spontaneous, dominant, genetic mutation in human beings, with complete penetrance, despite having variable expression. Incidence of NF1 is approximately 1:2500 newborns, affecting all races and having identical correlation between men and women.

PREVALENCE OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOR IN CHILDREN AND ADOLESCENTS WITH TYPE I NEUROFIBROMATOSIS

Purpose:

Type I neurofibromatosis (NF1) is considered the most common “new” spontaneous, dominant, genetic mutation in human beings, with complete penetrance, despite having variable expression. Incidence of NF1 is approximately 1:2500 newborns, affecting all races and having identical correlation between men and women. The malignant peripheral nerve sheath tumor (MPNST) accounts for 2–10% of all malignant soft tissue tumors.

Leia o Artigo completo através do link a seguir (necessário o programa Acrobat Reader – documento em PDF):

http://cnnf.org.br/portalnf/images/artigos/18/prevalence_of_malignant.pdf

 
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